About

The gnomAD Carrier Frequency Calculator is an open-source research tool for calculating carrier frequencies and recurrence risks of autosomal recessive conditions from gnomAD population data.

The Project

Built for research and educational use, the calculator queries the Genome Aggregation Database (gnomAD) directly from the browser and generates documentation text in German and English. It is designed for researchers and geneticists exploring carrier frequencies for autosomal recessive conditions. No server-side processing is required - all calculations run locally in the browser. This tool is not a validated clinical diagnostic tool; any outputs must be independently verified by qualified professionals.

Links

• GitHub Repository - Source code and issue tracker
• Open Calculator - Launch the calculator
• Getting Started - Walkthrough for new users

This Section

• Citation - How to cite the calculator in publications
• Changelog - Version history and release notes
• Contributing - Development setup and contribution guide

License

The gnomAD Carrier Frequency Calculator is released under the MIT License.